Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.

Shaping fission yeast cells by rerouting actin-based transport on microtubules.

Target of rapamycin (TOR) in nutrient signaling and growth control.

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.

Crystal structure of a multidomain human p53 tetramer bound to the natural CDKN1A (p21) p53-response element.

Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae.

Regulation of small GTPases at epithelial cell-cell junctions.

Three dimensional morphology of rabies virus studied by cryo-electron tomography.

Deconstructing the cell cycle.

Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress.

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L.

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis.

Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein.

A phosphorylation cycle shapes gradients of the DYRK family kinase Pom1 at the plasma membrane.

An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity.

A role for ZO-1 and PLEKHA7 in recruiting paracingulin to tight and adherens junctions of epithelial cells.

Genomic instability in induced stem cells.

A brief history of TOR.

SAHF, to senesce or not to senesce?

Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a Piwi protein.

Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions.

Chemical biology approaches to membrane homeostasis and function.

Actin cables and the exocyst form two independent morphogenesis pathways in the fission yeast.

Artificial tethering of Argonaute proteins for studying their role in translational repression of target mRNAs.