Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.

Glutamylation imbalance impairs the molecular architecture of the photoreceptor cilium.

Cryo-EM structures of apo-APC/C and APC/C(CDH1:EMI1) complexes provide insights into APC/C regulation.

Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay.

Telomeric transposons are pervasive in linear bacterial genomes.

Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains.

Racing through C. elegans mitosis using cyclin B3.

In vivo DNA replication dynamics unveil aging-dependent replication stress.

A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function.

A novel mitochondrial pyruvate carrier inhibitor drives stem cell-like memory CAR T cell generation and enhances antitumor efficacy.

Evidence for an interaction of paracingulin with microtubules.

Structural basis of μ-opioid receptor targeting by a nanobody antagonist.

Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival.

Cingulin-nonmuscle myosin interaction plays a role in epithelial morphogenesis and cingulin nanoscale organization.

Mesoscale molecular assembly is favored by the active, crowded cytoplasm.

Roles of N(6)-methyladenosine writers, readers and erasers in the mammalian germline.

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.

The molecular architecture of the ciliary transition zones.

Ultrastructure Expansion Microscopy applied to C. elegans embryos.

Mutational biases favor complexity increases in protein interaction networks after gene duplication.

A short guide to the tight junction.

Time-series reconstruction of the molecular architecture of human centriole assembly.

RECQL4 is not critical for firing of human DNA replication origins.

Fine-tuning FAM161A gene augmentation therapy to restore retinal function.

Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast

Transcription-replication conflicts underlie sensitivity to PARP inhibitors.

Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse.

An atlas of protein homo-oligomerization across domains of life.

Homozygous substitution of threonine 191 by proline in polymerase η causes Xeroderma pigmentosum variant.

S100A9 exerts insulin-independent antidiabetic and anti-inflammatory effects.