Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.

A Taybi-Linder syndrome-related RTTN variant impedes neural rosette formation in human cortical organoids.

Glutamylation imbalance impairs the molecular architecture of the photoreceptor cilium.

Cryo-EM structures of apo-APC/C and APC/C^CDH1:EMI1 complexes provide insights into APC/C regulation.

Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay.

Telomeric transposons are pervasive in linear bacterial genomes.

Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains.

Racing through C. elegans mitosis using cyclin B3.

In vivo DNA replication dynamics unveil aging-dependent replication stress.

The phase separation landscape of genome-wide genetic perturbations

A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function.

A novel mitochondrial pyruvate carrier inhibitor drives stem cell-like memory CAR T cell generation and enhances antitumor efficacy.

Evidence for an interaction of paracingulin with microtubules.

Structural basis of μ-opioid receptor targeting by a nanobody antagonist.

The A-C Linker controls centriole cohesion and duplication

TheC. eleganshomolog of Sjögren’s Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assembly

Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival.

Cingulin-nonmuscle myosin interaction plays a role in epithelial morphogenesis and cingulin nanoscale organization.

Mesoscale molecular assembly is favored by the active, crowded cytoplasm.

Roles of N(6)-methyladenosine writers, readers and erasers in the mammalian germline.

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.

The molecular architecture of the ciliary transition zones.

A phosphate-binding pocket in cyclin B3 is essential for XErp1/ Emi2 degradation in meiosis I

Ultrastructure Expansion Microscopy applied to C. elegans embryos.

Mutational biases favor complexity increases in protein interaction networks after gene duplication.

A short guide to the tight junction.

Time-series reconstruction of the molecular architecture of human centriole assembly.

Glutamylation imbalance leads to photoreceptor cell degeneration

A TALS-likeRTTNmutation impedes neural rosette formation in human cortical organoids

RECQL4 is not critical for firing of human DNA replication origins.

Fine-tuning FAM161A gene augmentation therapy to restore retinal function.

Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast

Transcription-replication conflicts underlie sensitivity to PARP inhibitors.

Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse.

An atlas of protein homo-oligomerization across domains of life.

Homozygous substitution of threonine 191 by proline in polymerase η causes Xeroderma pigmentosum variant.

S100A9 exerts insulin-independent antidiabetic and anti-inflammatory effects.