Retrotransposon silencing by piRNAs: ping-pong players mark their sub-cellular boundaries.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2009
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.
Geometric control of the cell cycle.
Emerging common themes in regulation of PIKKs and PI3Ks.
Pob1 participates in the Cdc42 regulation of fission yeast actin cytoskeleton.
The Vam6 GEF controls TORC1 by activating the EGO complex.
Helicobacter Pylori's plasticity zones are novel transposable elements.
Cyclic olefin homopolymer-based microfluidics for protein crystallization and in situ X-ray diffraction.
Microtubule-dependent cell morphogenesis in the fission yeast.
Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.
Microcollimator for micrometer-wide stripe irradiation of cells using 20-30 keV X rays.
Involvement of HFq protein in the post-transcriptional regulation of E. coli bacterial cytoskeleton and cell division proteins.
Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas.
Shaping fission yeast with microtubules.
Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins.
Resetting the site: redirecting integration of an insertion sequence in a predictable way.
Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle.
LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye.
Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile.
The tight junction protein cingulin regulates gene expression and RhoA signaling.
Weak functional constraints on phosphoproteomes.
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.
Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling.
Self-assembly and evolution of homomeric protein complexes.
Molecular shape and prominent role of beta-strand swapping in organization of dUTPase oligomers.
How perfect can protein interactomes be?
Visualization of proteins in intact cells with a clonable tag for electron microscopy.
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks.
Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response.
RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans.