Not Going with the Flow: How Cells Adapt Internal Physics.
Garcia-Seisdedos H , Heidenreich M , Levy ED
Cell
2020 Dec 10 ;
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Loss of histone H3.3 results in DNA replication defects and altered origin dynamics in C. elegans.
Strobino M , Wenda JM , Padayachy L , Steiner FA
Genome Res
2020 Dec ;
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Architecture of the centriole cartwheel-containing region revealed by cryo-electron tomography.
Klena N , Le Guennec M , Tassin AM , van den Hoek H , Erdmann PS , Schaffer M , Geimer S , Aeschlimann G , Kovacik L , Sadian Y , Goldie KN , Stahlberg H , Engel BD , Hamel V , Guichard P
EMBO J
2020 Nov 16 ;
39
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Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography.
Nazarov S , Bezler A , Hatzopoulos GN , Nemčíková Villímová V , Demurtas D , Le Guennec M , Guichard P , Gönczy P
EMBO J
2020 Nov 16 ;
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Resolving the Communication GAPs Upstream of TORC1.
Puschmann R , Loewith R
Dev Cell
2020 Nov 9 ;
55
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High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing.
Macheret M , Bhowmick R , Sobkowiak K , Padayachy L , Mailler J , Hickson ID , Halazonetis TD
Cell Res
2020 Nov ;
30
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997 -
1008
The tight junction protein cingulin regulates the vascular response to burn injury in a mouse model.
Zhuravleva K , Goertz O , Wölkart G , Guillemot L , Petzelbauer P , Lehnhardt M , Schmidt K , Citi S , Schossleitner K
Microvasc Res
2020 Nov ;
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Scaffolding proteins of vertebrate apical junctions: structure, functions and biophysics.
Rouaud F , Sluysmans S , Flinois A , Shah J , Vasileva E , Citi S
Biochim Biophys Acta Biomembr
2020 Oct 1 ;
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WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity.
Steib E , Laporte MH , Gambarotto D , Olieric N , Zheng C , Borgers S , Olieric V , Le Guennec M , Koll F , Tassin AM , Steinmetz MO , Guichard P , Hamel V
Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast.
Lamas I , Weber N , Martin SG
Cells
2020 Sep 12 ;
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Draining the FEN1s for cancer therapy.
Rossetti GG , Sotiriou SK , Halazonetis TD
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2020 Sep 8 ;
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Adaptations for centromere function in meiosis.
Prosée RF , Wenda JM , Steiner FA
Essays Biochem
2020 Sep 4 ;
64
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Designer protein assemblies with tunable phase diagrams in living cells.
Heidenreich M , Georgeson JM , Locatelli E , Rovigatti L , Nandi SK , Steinberg A , Nadav Y , Shimoni E , Safran SA , Doye JPK , Levy ED
Nat Chem Biol
2020 Sep ;
16
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TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast.
Schmidt O , Weyer Y , Sprenger S , Widerin MA , Eising S , Baumann V , Angelova M , Loewith R , Stefan CJ , Hess MW , Fröhlich F , Teis D
J Biol Chem
2020 Aug 21 ;
295
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The Mammalian Cap-Specific m(6)Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues.
Pandey RR , Delfino E , Homolka D , Roithova A , Chen KM , Li L , Franco G , Vågbø CB , Taillebourg E , Fauvarque MO , Pillai RS
Cell Rep
2020 Aug 18 ;
32
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Structural Insights into TOR Signaling.
Tafur L , Kefauver J , Loewith R
Genes (Basel)
2020 Aug 4 ;
11
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Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33.
Rouaud F , Tessaro F , Aimaretti L , Scapozza L , Citi S
J Biol Chem
2020 Jul 10 ;
295
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28 ):
9299 -
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Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Chang L , Yang J , Jo CH , Boland A , Zhang Z , McLaughlin SH , Abu-Thuraia A , Killoran RC , Smith MJ , Côté JF , Barford D
Nat Commun
2020 Jul 10 ;
11
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Proteomic analysis reveals the direct recruitment of intrinsically disordered regions to stress granules in S. cerevisiae.
Zhu M , Kuechler ER , Zhang J , Matalon O , Dubreuil B , Hofmann A , Loewen C , Levy ED , Gsponer J , Mayor T
J Cell Sci
2020 Jul 9 ;
133
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Molecular resolution imaging by post-labeling expansion single-molecule localization microscopy (Ex-SMLM).
Zwettler FU , Reinhard S , Gambarotto D , Bell TDM , Hamel V , Guichard P , Sauer M
Nat Commun
2020 Jul 7 ;
11
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Homogeneous multifocal excitation for high-throughput super-resolution imaging.
Mahecic D , Gambarotto D , Douglass KM , Fortun D , Banterle N , Ibrahim KA , Le Guennec M , Gönczy P , Hamel V , Guichard P , Manley S
Nat Methods
2020 Jul ;
17
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Native Architecture of the Centriole Proximal Region Reveals Features Underlying Its 9-Fold Radial Symmetry.
Guichard P , Hachet V , Majubu N , Neves A , Demurtas D , Olieric N , Fluckiger I , Yamada A , Kihara K , Nishida Y , Moriya S , Steinmetz MO , Hongoh Y , Gönczy P
Curr Biol
2020 Jun 8 ;
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TEX15 associates with MILI and silences transposable elements in male germ cells.
Yang F , Lan Y , Pandey RR , Homolka D , Berger SL , Pillai RS , Bartolomei MS , Wang PJ
Genes Dev
2020 Jun 1 ;
34
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Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition.
Marek M , Vincenzetti V , Martin SG
J Cell Biol
2020 Jun 1 ;
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The flipside of the TOR coin - TORC2 and plasma membrane homeostasis at a glance.
Riggi M , Kusmider B , Loewith R
J Cell Sci
2020 May 11 ;
133
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Essential function of the alveolin network in the subpellicular microtubules and conoid assembly in Toxoplasma gondii.
Tosetti N , Dos Santos Pacheco N , Bertiaux E , Maco B , Bournonville L , Hamel V , Guichard P , Soldati-Favre D
Tubulin Resists Degradation by Cereblon-Recruiting PROTACs.
Gasic I , Groendyke BJ , Nowak RP , Yuan JC , Kalabathula J , Fischer ES , Gray NS , Mitchison TJ
Cells
2020 Apr 27 ;
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DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division.
Bhattacharjee R , Mangione MC , Wos M , Chen JS , Snider CE , Roberts-Galbraith RH , McDonald NA , Presti LL , Martin SG , Gould KL
Mol Biol Cell
2020 Apr 15 ;
31
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Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9.
Plank M , Perepelkina M , Müller M , Vaga S , Zou X , Bourgoint C , Berti M , Saarbach J , Haesendonckx S , Winssinger N , Aebersold R , Loewith R
Mol Cell Proteomics
2020 Apr ;
19
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The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast.
Serbyn N , Noireterre A , Bagdiul I , Plank M , Michel AH , Loewith R , Kornmann B , Stutz F
Mol Cell
2020 Mar 5 ;
77
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5 ):
1066 -
1079.e9
A helical inner scaffold provides a structural basis for centriole cohesion.
Le Guennec M , Klena N , Gambarotto D , Laporte MH , Tassin AM , van den Hoek H , Erdmann PS , Schaffer M , Kovacik L , Borgers S , Goldie KN , Stahlberg H , Bornens M , Azimzadeh J , Engel BD , Hamel V , Guichard P
Sci Adv
2020 Feb ;
6
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Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase.
Lamas I , Merlini L , Vještica A , Vincenzetti V , Martin SG
PLoS Biol
2020 Jan ;
18
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e3000600
Cell Biology: Tight Junctions as Biomolecular Condensates.
Citi S
Curr Biol
2020 Jan 20 ;
30
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R86
A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.
Kesselring L , Miskey C , Zuliani C , Querques I , Kapitonov V , Laukó A , Fehér A , Palazzo A , Diem T , Lustig J , Sebe A , Wang Y , Dinnyés A , Izsvák Z , Barabas O , Ivics Z
Nucleic Acids Res
2020 Jan 10 ;
48
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A toolbox of stable integration vectors in the fission yeast Schizosaccharomyces pombe.
Vještica A , Marek M , Nkosi PJ , Merlini L , Liu G , Bérard M , Billault-Chaumartin I , Martin SG
J Cell Sci
2020 Jan 8 ;
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PDBe-KB: a community-driven resource for structural and functional annotations.
PDBe-KB consortium
Nucleic Acids Res
2020 Jan 8 ;
48
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TTC5 mediates autoregulation of tubulin via mRNA degradation.
Lin Z , Gasic I , Chandrasekaran V , Peters N , Shao S , Mitchison TJ , Hegde RS
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2020 Jan 3 ;
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