An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2014
Structure of an Escherichia coli Hfq:RNA complex at 0.97 Å resolution.
Acta Crystallogr F Struct Biol Commun,
2014 Nov;
70
(Pt 11): 1492-1497
Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis.
Fly piRNA biogenesis: tap dancing with Tej.
Primary piRNA biogenesis: caught up in a Maelstrom.
Fast and accurate discovery of degenerate linear motifs in protein sequences.
Correlative multicolor 3D SIM and STORM microscopy.
ZO proteins redundantly regulate the transcription factor DbpA/ZONAB.
Pom1 regulates the assembly of Cdr2-Mid1 cortical nodes for robust spatial control of cytokinesis.
MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly.
RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts.
A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.
The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs.
Impact of nuclear Piwi elimination on chromatin state in Drosophila melanogaster ovaries.
Different subunits belonging to the same protein complex often exhibit discordant expression levels and evolutionary properties.
High-resolution mapping of protein concentration reveals principles of proteome architecture and adaptation.
Toll-like receptor 2 regulates the barrier function of human bronchial epithelial monolayers through atypical protein kinase C zeta, and an increase in expression of claudin-1.
The novel proteins Rng8 and Rng9 regulate the myosin-V Myo51 during fission yeast cytokinesis.
Conservative DNA replication.
The Tea4-PP1 landmark promotes local growth by dual Cdc42 GEF recruitment and GAP exclusion.
Roles for PI(3,5)P2 in nutrient sensing through TORC1.
Yeasts as models in cell biology.
Cell polarization in budding and fission yeasts.
Reversal of the DNA-binding-induced loop L1 conformational switch in an engineered human p53 protein.
PARP inhibitors and IR join forces to strike glioblastoma-initiating cells.
Break-induced replication repair of damaged forks induces genomic duplications in human cells.
A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast.
Holocentromeres are dispersed point centromeres localized at transcription factor hotspots.
Analysis of small RNA-guided endonuclease activity in endogenous Piwi protein complexes from mouse testes.
Epithelial junctions and Rho family GTPases: the zonular signalosome.
PLEKHA7 modulates epithelial tight junction barrier function.
Distinct levels in Pom1 gradients limit Cdr2 activity and localization to time and position division.