Publications

Publications from current research groups. For publications from former groups, see alumni pages

2014

An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.
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Nucleic Acids Res, ; 42 (22): 13525-13533
Structure of an Escherichia coli Hfq:RNA complex at 0.97 Å resolution.
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Acta Crystallogr F Struct Biol Commun, ; 70 (Pt 11): 1492-1497
Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis.
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Mol Biol Cell, ; 25 (20): 3234-3246
Primary piRNA biogenesis: caught up in a Maelstrom.
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EMBO J, ; 33 (18): 1979-1980
Fast and accurate discovery of degenerate linear motifs in protein sequences.
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PLoS One, ; 9 (9): e106081
Correlative multicolor 3D SIM and STORM microscopy.
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Biomed Opt Express, ; 5 (10): 3326-3336
ZO proteins redundantly regulate the transcription factor DbpA/ZONAB.
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J Biol Chem, ; 289 (32): 22500-22511
Pom1 regulates the assembly of Cdr2-Mid1 cortical nodes for robust spatial control of cytokinesis.
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J Cell Biol, ; 206 (1): 61-77
MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly.
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Mol Biol Cell, ; 25 (13): 1995-2005
RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts.
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Cell, ; 157 (7): 1698-1711
A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.
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Mol Cell, ; 54 (5): 737-750
The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs.
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RNA, ; 20 (6): 773-781
Impact of nuclear Piwi elimination on chromatin state in Drosophila melanogaster ovaries.
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Nucleic Acids Res, ; 42 (10): 6208-6218
Different subunits belonging to the same protein complex often exhibit discordant expression levels and evolutionary properties.
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Curr Opin Struct Biol, ; 26 : 113-120
High-resolution mapping of protein concentration reveals principles of proteome architecture and adaptation.
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Cell Rep, ; 7 (4): 1333-1340
Toll-like receptor 2 regulates the barrier function of human bronchial epithelial monolayers through atypical protein kinase C zeta, and an increase in expression of claudin-1.
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Tissue Barriers, ; 2 : e29166
The novel proteins Rng8 and Rng9 regulate the myosin-V Myo51 during fission yeast cytokinesis.
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J Cell Biol, ; 205 (3): 357-375
Conservative DNA replication.
Nat Rev Mol Cell Biol, ; 15 (5): 300
The Tea4-PP1 landmark promotes local growth by dual Cdc42 GEF recruitment and GAP exclusion.
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J Cell Sci, ; 127 (Pt 9): 2005-2016
Roles for PI(3,5)P2 in nutrient sensing through TORC1.
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Mol Biol Cell, ; 25 (7): 1171-1185
Yeasts as models in cell biology.
FEMS Microbiol Rev, ; 38 (2): 143
Cell polarization in budding and fission yeasts.
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FEMS Microbiol Rev, ; 38 (2): 228-253
Reversal of the DNA-binding-induced loop L1 conformational switch in an engineered human p53 protein.
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J Mol Biol, ; 426 (4): 936-944
PARP inhibitors and IR join forces to strike glioblastoma-initiating cells.
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Cell Death Differ, ; 21 (2): 192-193
Break-induced replication repair of damaged forks induces genomic duplications in human cells.
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Science, ; 343 (6166): 88-91
A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast.
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PLoS Genet, ; 10 (1): e1004010
Holocentromeres are dispersed point centromeres localized at transcription factor hotspots.
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Elife, ; 3 : e02025
Analysis of small RNA-guided endonuclease activity in endogenous Piwi protein complexes from mouse testes.
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Methods Mol Biol, ; 1093 : 111-121
Epithelial junctions and Rho family GTPases: the zonular signalosome.
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Small GTPases, ; 5 (4): 1-15
PLEKHA7 modulates epithelial tight junction barrier function.
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Tissue Barriers, ; 2 (1): e28755
Distinct levels in Pom1 gradients limit Cdr2 activity and localization to time and position division.
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Cell Cycle, ; 13 (4): 538-552