Regulation of Cellular Metabolism through Phase Separation of Enzymes.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2018
Differential GAP requirement for Cdc42-GTP polarization during proliferation and sexual reproduction.
Effects of stably incorporated iron on protein phosphatase-1 structure and activity.
The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1.
A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity.
Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles.
Methylation of Structured RNA by the m(6)A Writer METTL16 Is Essential for Mouse Embryonic Development.
Exonuclease Domain-Containing 1 Enhances MIWI2 piRNA Biogenesis via Its Interaction with TDRD12.
Decrease in plasma membrane tension triggers PtdIns(4,5)P(2) phase separation to inactivate TORC2.
Gamete fusion triggers bipartite transcription factor assembly to block re-fertilization.
Genome-wide C-SWAT library for high-throughput yeast genome tagging.
Genome-wide SWAp-Tag yeast libraries for proteome exploration.
Exploration and stabilization of Ras1 mating zone: A mechanism with positive and negative feedbacks.
Target of rapamycin complex 2-dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae.
Differential Expression of Histone H3.3 Genes and Their Role in Modulating Temperature Stress Response in Caenorhabditis elegans.
Dynamic visits of cortical structures probe for cell size.
Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering.
Reconstruction From Multiple Particles for 3D Isotropic Resolution in Fluorescence Microscopy.
Systematic analysis of complex genetic interactions.
Inhibition of Ras activity coordinates cell fusion with cell-cell contact during yeast mating.
Super-resolution microscopy to decipher multi-molecular assemblies.
The Rise of the Cartwheel: Seeding the Centriole Organelle.
Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
Intestinal barriers protect against disease.
Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress.
Conjugative transposition of the vancomycin resistance carrying Tn1549: enzymatic requirements and target site preferences.
The role of microtubules in the regulation of epithelial junctions.
Inferring and Using Protein Quaternary Structure Information from Crystallographic Data.
PDB-wide identification of biological assemblies from conserved quaternary structure geometry.