Histone deacetylase inhibitors up-regulate the expression of tight junction proteins.

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks.

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression.

Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase.

Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis.

The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein.

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.

Constitutively active DNA damage checkpoint pathways as the driving force for the high frequency of p53 mutations in human cancer.

53BP1, an activator of ATM in response to DNA damage.

Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1.

Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.

p53 and stress in the ER.