Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2004
Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase.
Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis.
The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein.
Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.