Publications

Publications from current research groups. For publications from former groups, see alumni pages

2022

Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast.
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J Cell Sci, ; 135 (24)
Molecular and environmental determinants of biomolecular condensate formation.
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Nat Chem Biol, ; 18 (12): 1319-1329
Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion.
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Curr Biol, ; 32 (21): 4752-4761.e10
Human SFI1 and Centrin form a complex critical for centriole architecture and ciliogenesis.
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EMBO J, ; 41 (21): e112107
Cryo-EM structure of the SEA complex.
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Nature, ; 611 (7935): 399-404
Structural biology of DOCK-family guanine nucleotide exchange factors.
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FEBS Lett, ; 597 (6): 794-810
How gene duplication diversifies the landscape of protein oligomeric state and function.
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Curr Opin Genet Dev, ; 76 : 101966
Recurrent but Short-Lived Duplications of Centromeric Proteins in Holocentric Caenorhabditis Species.
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Mol Biol Evol, ; 39 (10)
Affinity and Valence Impact the Extent and Symmetry of Phase Separation of Multivalent Proteins.
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Phys Rev Lett, ; 129 (12): 128102
mNG-tagged fusion proteins and nanobodies to visualize tropomyosins in yeast and mammalian cells.
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J Cell Sci, ; 135 (18)
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells.
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Mol Cell, ; 82 (18): 3382-3397.e7
RAD51 protects human cells from transcription-replication conflicts.
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Mol Cell, ; 82 (18): 3366-3381.e9
The evolutionary conserved proteins CEP90, FOPNL, and OFD1 recruit centriolar distal appendage proteins to initiate their assembly.
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PLoS Biol, ; 20 (9): e3001782
CEMIP (HYBID, KIAA1199): structure, function and expression in health and disease.
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FEBS J, ; 290 (16): 3946-3962
The PLEKHA7-PDZD11 complex regulates the localization of the calcium pump PMCA and calcium handling in cultured cells.
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J Biol Chem, ; 298 (8): 102138
In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains.
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Science, ; 377 (6605): 543-548
Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis.
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Nat Commun, ; 13 (1): 4107
Transmission of chromatin states across generations in C. elegans.
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Semin Cell Dev Biol, ; 127 : 133-141
Actin assembly requirements of the formin Fus1 to build the fusion focus.
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J Cell Sci, ; 135 (13)
A unified statistical potential reveals that amino acid stickiness governs nonspecific recruitment of client proteins into condensates.
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Protein Sci, ; 31 (7): e4361
The connecting cilium inner scaffold provides a structural foundation that protects against retinal degeneration.
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PLoS Biol, ; 20 (6): e3001649
Synthetic condensate size correlates with yeast replicative cell age.
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MicroPubl Biol, ; 2022
Regulation of Tubulin Gene Expression: From Isotype Identity to Functional Specialization.
Front Cell Dev Biol, ; 10 : 898076
The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m(6)A recognition.
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Mol Cell, ; 82 (9): 1678-1690.e12
Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes.
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Nucleic Acids Res, ; 50 (6): 3155-3168
Cingulin binds to the ZU5 domain of scaffolding protein ZO-1 to promote its extended conformation, stabilization, and tight junction accumulation.
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J Biol Chem, ; 298 (4): 101797
Engineered Sleeping Beauty transposase redirects transposon integration away from genes.
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Nucleic Acids Res, ; 50 (5): 2807-2825
The modular cell gets connected.
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Science, ; 375 (6585): 1093-1094
Non-covalent SARS-CoV-2 M(pro) inhibitors developed from in silico screen hits.
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Sci Rep, ; 12 (1): 2505
The ACE2 Receptor for Coronavirus Entry Is Localized at Apical Cell-Cell Junctions of Epithelial Cells.
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Cells, ; 11 (4)
Beating cancer one carbon at a time.
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Nat Cancer, ; 3 (2): 141-142
Visualizing the native cellular organization by coupling cryofixation with expansion microscopy (Cryo-ExM).
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Nat Methods, ; 19 (2): 216-222
Mutant libraries reveal negative design shielding proteins from supramolecular self-assembly and relocalization in cells.
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Proc Natl Acad Sci U S A, ; 119 (5)
PDBe-KB: collaboratively defining the biological context of structural data.
Nucleic Acids Res, ; 50 (D1): D534-D542
QSalignWeb: A Server to Predict and Analyze Protein Quaternary Structure.
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Front Mol Biosci, ; 8 : 787510