Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2008
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
Caffeine extends yeast lifespan by targeting TORC1.
Assembly reflects evolution of protein complexes.
Evolution and dynamics of protein interactions and networks.
Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
An oncogene-induced DNA damage model for cancer development.
The cytoplasmic plaque of tight junctions: a scaffolding and signalling center.
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.
In vitro reconstitution of a single-stranded transposition mechanism of IS608.
Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection.
Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression.