Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2008
Caffeine extends yeast lifespan by targeting TORC1.
Assembly reflects evolution of protein complexes.
Evolution and dynamics of protein interactions and networks.
Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
An oncogene-induced DNA damage model for cancer development.
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.
In vitro reconstitution of a single-stranded transposition mechanism of IS608.
Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection.