Publications

Publications from current research groups. For publications from former groups, see alumni pages

2008

Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
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Biochem Biophys Res Commun, ; 373 (1): 8-13
Caffeine extends yeast lifespan by targeting TORC1.
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Mol Microbiol, ; 69 (1): 277-285
Assembly reflects evolution of protein complexes.
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Nature, ; 453 (7199): 1262-1265
Evolution and dynamics of protein interactions and networks.
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Curr Opin Struct Biol, ; 18 (3): 349-357
Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
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Proteins, ; 71 (1): 308-319
An oncogene-induced DNA damage model for cancer development.
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Science, ; 319 (5868): 1352-1355
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.
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Mol Immunol, ; 45 (6): 1752-1760
In vitro reconstitution of a single-stranded transposition mechanism of IS608.
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Mol Cell, ; 29 (3): 302-312
Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection.
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Cell, ; 132 (2): 208-220