Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2016
Role and organization of the actin cytoskeleton during cell-cell fusion.
Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation.
Structure of centromere chromatin: from nucleosome to chromosomal architecture.
Protein-Fragment Complementation Assays for Large-Scale Analysis, Functional Dissection, and Spatiotemporal Dynamic Studies of Protein-Protein Interactions in Living Cells.
The Dihydrofolate Reductase Protein-Fragment Complementation Assay: A Survival-Selection Assay for Large-Scale Analysis of Protein-Protein Interactions.
Young phosphorylation is functionally silent.
The Ska complex promotes Aurora B activity to ensure chromosome biorientation.
Dual action antifungal small molecule modulates multidrug efflux and TOR signaling.
Spatial focalization of pheromone/MAPK signaling triggers commitment to cell-cell fusion.
Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice.
The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding.
Structural Determinants of Sleeping Beauty Transposase Activity.
Evolution of domain-peptide interactions to coadapt specificity and affinity to functional diversity.
Computational support for a scaffolding mechanism of centriole assembly.
Corrigendum: SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
TORC2 Structure and Function.
Local Pheromone Release from Dynamic Polarity Sites Underlies Cell-Cell Pairing during Yeast Mating.
SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering.
Microscopy of Fission Yeast Sexual Lifecycle.
Basal body structure in Trichonympha.
Cell type-specific epigenome profiling using affinity-purified nuclei.
A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction.
PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway.