Acquisition of an Archaea-like ribonuclease H domain by plant L1 retrotransposons supports modular evolution.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2013
Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling.
Extracting insight from noisy cellular networks.
Structure and assembly of the NOT module of the human CCR4-NOT complex.
Nonautonomous movement of chromosomes in mitosis.
Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.
Hepatitis B subvirus particles display both a fluid bilayer membrane and a strong resistance to freeze drying: a study by solid-state NMR, light scattering, and cryo-electron microscopy/tomography.
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks.
Native architecture of the centriole proximal region reveals features underlying its 9-fold radial symmetry.
Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins.
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.
A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response.
Growth control: function follows form.
Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
An atomistic view of microtubule stabilization by GTP.
[The piRNAs forge an immune system for the genome].
Use of red autofluorescence for monitoring prodiginine biosynthesis.
Mate and fuse: how yeast cells do it.
Cdc42 explores the cell periphery for mate selection in fission yeast.
Ultraviolet-B-mediated induction of protein-protein interactions in mammalian cells.
The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4.
Structural, evolutionary, and assembly principles of protein oligomerization.