Publications

Publications from current research groups. For publications from former groups, see alumni pages

2021

Chemical-Biology-derived in vivo Sensors: Past, Present, and Future.
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Chimia (Aarau), ; 75 (12): 1017-1021
Flipper Probes for the Community.
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Chimia (Aarau), ; 75 (12): 1004-1011
YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis.
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Cell Rep, ; 37 (11): 110110
The centriolar tubulin code.
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Semin Cell Dev Biol, ; 137 : 16-25
Mitotic chromosome condensation requires phosphorylation of the centromeric protein KNL-2 in C. elegans.
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J Cell Sci, ; 134 (23)
Passive coupling of membrane tension and cell volume during active response of cells to osmosis.
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Proc Natl Acad Sci U S A, ; 118 (47)
Going with the membrane flow: the impact of polarized secretion on bulk plasma membrane flows.
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FEBS J, ; 290 (3): 669-676
The FASTK family proteins fine-tune mitochondrial RNA processing.
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PLoS Genet, ; 17 (11): e1009873
PDB-wide identification of physiological hetero-oligomeric assemblies based on conserved quaternary structure geometry.
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Structure, ; 29 (11): 1303-1311.e3
PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis.
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Mol Biol Cell, ; 32 (21): ar34
Altered Protein Abundance and Localization Inferred from Sites of Alternative Modification by Ubiquitin and SUMO.
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J Mol Biol, ; 433 (21): 167219
Ultrastructural plasma membrane asymmetries in tension and curvature promote yeast cell fusion.
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J Cell Biol, ; 220 (10)
Delayed DNA break repair for genome stability.
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Nat Cell Biol, ; 23 (10): 1055-1057
Deciphering the modes of human separase inhibition by securin and CDK1-CCNB1.
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Mol Cell Oncol, ; 8 (4): 1975473
Cell patterning by secretion-induced plasma membrane flows.
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Sci Adv, ; 7 (38): eabg6718
Correction: Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid.
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PLoS Biol, ; 19 (9): e3001401
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.
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Elife, ; 10
WW, PH and C-Terminal Domains Cooperate to Direct the Subcellular Localizations of PLEKHA5, PLEKHA6 and PLEKHA7.
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Front Cell Dev Biol, ; 9 : 729444
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells.
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Nat Commun, ; 12 (1): 4919
Structural basis of human separase regulation by securin and CDK1-cyclin B1.
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Nature, ; 596 (7870): 138-142
Transgenerational inheritance of centromere identity requires the CENP-A N-terminal tail in the C. elegans maternal germ line.
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PLoS Biol, ; 19 (7): e3000968
Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides.
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ACS Cent Sci, ; 7 (6): 954-962
Splice site m(6)A methylation prevents binding of U2AF35 to inhibit RNA splicing.
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Cell, ; 184 (12): 3125-3142.e25
Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes.
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Mol Syst Biol, ; 17 (5): e9880
Abundance Imparts Evolutionary Constraints of Similar Magnitude on the Buried, Surface, and Disordered Regions of Proteins.
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Front Mol Biosci, ; 8 : 626729
Direct and indirect regulation of Pom1 cell size pathway by the protein phosphatase 2C Ptc1.
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Mol Biol Cell, ; 32 (8): 703-711
Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes.
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Cancers (Basel), ; 13 (6)
Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid.
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PLoS Biol, ; 19 (3): e3001020
Characterization of the novel mitochondrial genome segregation factor TAP110 in Trypanosoma brucei.
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J Cell Sci, ; 134 (5)
Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation.
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Chembiochem, ; 22 (5): 834-838
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening.
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iScience, ; 24 (2): 102021
Overview of the centriole architecture.
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Curr Opin Struct Biol, ; 66 : 58-65
"Structuromics": another step toward a holistic view of the cell.
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Cell, ; 184 (2): 301-303
Cell cycle-dependent and independent mating blocks ensure fungal zygote survival and ploidy maintenance.
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PLoS Biol, ; 19 (1): e3001067
A method to sequence genomic sites of mitotic DNA synthesis in mammalian cells.
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Methods Enzymol, ; 661 : 283-304
Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55.
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Proteomics, ; 21 (1): e2000166
Ultrastructure expansion microscopy (U-ExM).
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Methods Cell Biol, ; 161 : 57-81
Improving the resolution of fluorescence nanoscopy using post-expansion labeling microscopy.
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Methods Cell Biol, ; 161 : 297-315