Chemical-Biology-derived in vivo Sensors: Past, Present, and Future.
Publications
Publications from current research groups. For publications from former groups, see alumni pages
2021
Flipper Probes for the Community.
YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis.
The centriolar tubulin code.
Mitotic chromosome condensation requires phosphorylation of the centromeric protein KNL-2 in C. elegans.
Passive coupling of membrane tension and cell volume during active response of cells to osmosis.
Going with the membrane flow: the impact of polarized secretion on bulk plasma membrane flows.
The FASTK family proteins fine-tune mitochondrial RNA processing.
PDB-wide identification of physiological hetero-oligomeric assemblies based on conserved quaternary structure geometry.
Altered Protein Abundance and Localization Inferred from Sites of Alternative Modification by Ubiquitin and SUMO.
SFI1 and centrin form a distal end complex critical for proper centriole architecture and ciliogenesis
Ultrastructural plasma membrane asymmetries in tension and curvature promote yeast cell fusion.
Deciphering the modes of human separase inhibition by securin and CDK1-CCNB1.
Cell patterning by secretion-induced plasma membrane flows.
Correction: Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid.
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.
The connecting cilium inner scaffold provides a structural foundation to maintain photoreceptor integrity
Structural basis of human separase regulation by securin and CDK1-cyclin B1.
Transgenerational inheritance of centromere identity requires the CENP-A N-terminal tail in the C. elegans maternal germ line.
Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides.
Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly.
Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing.
Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes.
Abundance Imparts Evolutionary Constraints of Similar Magnitude on the Buried, Surface, and Disordered Regions of Proteins.
Direct and indirect regulation of Pom1 cell size pathway by the protein phosphatase 2C Ptc1.
Experimental Evolution to Understand the Interplay Between Genetics and Adaptation
Evolutionary Systems Biology,
26 March 2021;
: Chapter 1
Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid.
Characterization of the novel mitochondrial genome segregation factor TAP110 in Trypanosoma brucei.
Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation.
Overview of the centriole architecture.
"Structuromics": another step toward a holistic view of the cell.
Cell cycle-dependent and independent mating blocks ensure fungal zygote survival and ploidy maintenance.
Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55.
Preface.
Ultrastructure expansion microscopy (U-ExM).
Improving the resolution of fluorescence nanoscopy using post-expansion labeling microscopy.