Explorers and Architects of Cells' Proteome
Life processes involve an intricate choreography between tens of millions of protein building blocks that form the infrastructure of cells. Recent technological advances have revealed the catalogs of proteins present in various cells and organisms. However, understanding how these protein building-blocks assemble and work together is an extraordinarily complex task.
The overarching goal of our research is to characterize the general principles by which proteins self-organize. In this endeavor, we integrate computational and experimental approaches: we combine high-content imaging with structural biology techniques, proteomics, genetic engineering, bioinformatics, and more. Our favorite pet is budding yeast.