Sandra Citi



Signaling by cell-cell junctions

The goal of our research is to understand the molecular mechanisms (control of Rho GTPases, transcription factors, transmembrane receptors, mechanodependent protein conformation, etc) through which cell-cell junctions regulate signaling, to control cytoskeletal organization, morphogenesis, proliferation, and many other aspects of cell behavior related to the physiology and pathology of tissues and organs. Junctions are particularly important in epithelial and endothelial cells, for cell adhesion, barrier function, communication, and control or organ growth and physiology. Epithelial and endothelial cells are also implicated in major diseases. Our laboratory uses many methodological approaches, including biochemistry, cell culture, and mouse models.

Sandra_Citi_2024.jpgSandra CITI, MD, PhD
Associate Professor
University of Geneva
Dept. of Molecular and Cellular Biology
Sc3 2018B
30, quai Ernest-Ansermet
CH-1211, Geneva 4, Switzerland
Tel: +41 22 379 61 82
Fax: +41 22 379 68 68