2024
S100A9 exerts insulin-independent antidiabetic and anti-inflammatory effects.
Ursino G , Lucibello G , Teixeira PDS , Höfler A , Veyrat-Durebex C , Odouard S , Visentin F , Galgano L , Somm E , Vianna CR , Widmer A , Jornayvaz FR , Boland A , Ramadori G , Coppari R
Sci Adv ,
2024 Jan 5 ;
10
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eadj4686
2023
Structural Basis of μ-Opioid Receptor-Targeting by a Nanobody Antagonist.
Yu J , Kumar A , Zhang X , Martin C , Raia P , Koehl A , Laeremans T , Steyaert J , Manglik A , Ballet S , Boland A , Stoeber M
The molecular mechanisms of human separase regulation.
Yu J , Morgan DO , Boland A
Biochem Soc Trans ,
2023 Jun 28 ;
51
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3 ):
1225 -
1233
2022
Structural biology of DOCK-family guanine nucleotide exchange factors.
Boland A , Côté JF , Barford D
FEBS Lett ,
2023 Mar ;
597
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6 ):
794 -
810
CEMIP (HYBID, KIAA1199): structure, function and expression in health and disease.
Spataro S , Guerra C , Cavalli A , Sgrignani J , Sleeman J , Poulain L , Boland A , Scapozza L , Moll S , Prunotto M
FEBS J ,
2023 Aug ;
290
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16 ):
3946 -
3962
Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis.
Ursino G , Ramadori G , Höfler A , Odouard S , Teixeira PDS , Visentin F , Veyrat-Durebex C , Lucibello G , Firnkes R , Ricci S , Vianna CR , Jia L , Dirlewanger M , Klee P , Elmquist JK , Roth J , Vogl T , Schwitzgebel VM , Jornayvaz FR , Boland A , Coppari R
Nat Commun ,
2022 Jul 15 ;
13
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1 ):
4107
2021
Deciphering the modes of human separase inhibition by securin and CDK1-CCNB1.
Raia P , Yu J , Boland A
Mol Cell Oncol ,
2021 ;
8
(
4 ):
1975473
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.
Heimhalt M , Berndt A , Wagstaff J , Anandapadamanaban M , Perisic O , Maslen S , McLaughlin S , Yu CW , Masson GR , Boland A , Ni X , Yamashita K , Murshudov GN , Skehel M , Freund SM , Williams RL
Structural basis of human separase regulation by securin and CDK1-cyclin B1.
Yu J , Raia P , Ghent CM , Raisch T , Sadian Y , Cavadini S , Sabale PM , Barford D , Raunser S , Morgan DO , Boland A
Nature ,
2021 Aug ;
596
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138 -
142
2020
Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Chang L , Yang J , Jo CH , Boland A , Zhang Z , McLaughlin SH , Abu-Thuraia A , Killoran RC , Smith MJ , Côté JF , Barford D
Nat Commun ,
2020 Jul 10 ;
11
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3464
2019
A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Kiss L , Zeng J , Dickson CF , Mallery DL , Yang JC , McLaughlin SH , Boland A , Neuhaus D , James LC
Nat Commun ,
2019 Oct 3 ;
10
(
1 ):
4502
2018
The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1.
Sosnowski P , Urnavicius L , Boland A , Fagiewicz R , Busselez J , Papai G , Schmidt H
2017
The potential of cryo-electron microscopy for structure-based drug design.
Boland A , Chang L , Barford D
Essays Biochem ,
2017 Nov 8 ;
61
(
5 ):
543 -
560
Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
Boland A , Martin TG , Zhang Z , Yang J , Bai XC , Chang L , Scheres SH , Barford D
Nat Struct Mol Biol ,
2017 Apr ;
24
(
4 ):
414 -
418
2015
Fast native-SAD phasing for routine macromolecular structure determination.
Weinert T , Olieric V , Waltersperger S , Panepucci E , Chen L , Zhang H , Zhou D , Rose J , Ebihara A , Kuramitsu S , Li D , Howe N , Schnapp G , Pautsch A , Bargsten K , Prota AE , Surana P , Kottur J , Nair DT , Basilico F , Cecatiello V , Pasqualato S , Boland A , Weichenrieder O , Wang BC , Steinmetz MO , Caffrey M , Wan
Nat Methods ,
2015 Feb ;
12
(
2 ):
131 -
133
2014
A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.
Chen Y , Boland A , Kuzuoğlu-Öztürk D , Bawankar P , Loh B , Chang CT , Weichenrieder O , Izaurralde E
Mol Cell ,
2014 Jun 5 ;
54
(
5 ):
737 -
750
2013
Structure and assembly of the NOT module of the human CCR4-NOT complex.
Boland A , Chen Y , Raisch T , Jonas S , Kuzuoğlu-Öztürk D , Wohlbold L , Weichenrieder O , Izaurralde E
Nat Struct Mol Biol ,
2013 Nov ;
20
(
11 ):
1289 -
1297
Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins.
Christie M , Boland A , Huntzinger E , Weichenrieder O , Izaurralde E
Mol Cell ,
2013 Aug 8 ;
51
(
3 ):
360 -
373
2012
A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation.
Braun JE , Truffault V , Boland A , Huntzinger E , Chang CT , Haas G , Weichenrieder O , Coles M , Izaurralde E
Nat Struct Mol Biol ,
2012 Dec ;
19
(
12 ):
1324 -
1331
2011
Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein.
Boland A , Huntzinger E , Schmidt S , Izaurralde E , Weichenrieder O
Proc Natl Acad Sci U S A ,
2011 Jun 28 ;
108
(
26 ):
10466 -
10471
2010
Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein.
Boland A , Tritschler F , Heimstädt S , Izaurralde E , Weichenrieder O
EMBO Rep ,
2010 Jul ;
11
(
7 ):
522 -
527