Andreas Boland

Publications

2024

S100A9 exerts insulin-independent antidiabetic and anti-inflammatory effects.
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Sci Adv, ; 10 (1): eadj4686

2023

Structural Basis of μ-Opioid Receptor-Targeting by a Nanobody Antagonist.
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bioRxiv, ;
The molecular mechanisms of human separase regulation.
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Biochem Soc Trans, ; 51 (3): 1225-1233

2022

Structural biology of DOCK-family guanine nucleotide exchange factors.
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FEBS Lett, ; 597 (6): 794-810
CEMIP (HYBID, KIAA1199): structure, function and expression in health and disease.
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FEBS J, ; 290 (16): 3946-3962
Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis.
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Nat Commun, ; 13 (1): 4107

2021

Deciphering the modes of human separase inhibition by securin and CDK1-CCNB1.
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Mol Cell Oncol, ; 8 (4): 1975473
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.
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Elife, ; 10
Structural basis of human separase regulation by securin and CDK1-cyclin B1.
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Nature, ; 596 (7870): 138-142

2020

Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
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Nat Commun, ; 11 (1): 3464

2019

A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
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Nat Commun, ; 10 (1): 4502

2018

The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1.
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Elife, ; 7

2017

The potential of cryo-electron microscopy for structure-based drug design.
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Essays Biochem, ; 61 (5): 543-560
Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
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Nat Struct Mol Biol, ; 24 (4): 414-418

2015

Fast native-SAD phasing for routine macromolecular structure determination.
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Nat Methods, ; 12 (2): 131-133

2014

A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.
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Mol Cell, ; 54 (5): 737-750

2013

Structure and assembly of the NOT module of the human CCR4-NOT complex.
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Nat Struct Mol Biol, ; 20 (11): 1289-1297
Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins.
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Mol Cell, ; 51 (3): 360-373

2012

A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation.
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Nat Struct Mol Biol, ; 19 (12): 1324-1331

2011

Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein.
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Proc Natl Acad Sci U S A, ; 108 (26): 10466-10471

2010

Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein.
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EMBO Rep, ; 11 (7): 522-527