Structure of the MIWI endoribonuclease bound to pachytene piRNAs from mouse testes

Roles of N⁶-methyladenosine writers, readers and erasers in the mammalian germline.

Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility.

The catalytic-dead Pcif1 regulates gene expression and fertility in Drosophila.

Intermitochondrial cement (IMC) harbors piRNA biogenesis machinery and exonuclease domain-containing proteins EXD1 and EXD2 in mouse spermatocytes.

In vivo PIWI slicing in mouse testes deviates from rules established in vitro.

The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m⁶A recognition.

YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis.

Splice site m⁶A methylation prevents binding of U2AF35 to inhibit RNA splicing.

The Mammalian Cap-Specific m⁶Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues.

TEX15 associates with MILI and silences transposable elements in male germ cells.

Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.

An RNA exporter that enforces a no-export policy.

Nxf3: a middleman with the right connections for unspliced piRNA precursor export.

Counting the Cuts: MAZTER-Seq Quantifies m⁶A Levels Using a Methylation-Sensitive Ribonuclease.

Methylation of Structured RNA by the m⁶A Writer METTL16 Is Essential for Mouse Embryonic Development.

Exonuclease Domain-Containing 1 Enhances MIWI2 piRNA Biogenesis via Its Interaction with TDRD12.

Regulation of m⁶A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.

Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.

Recruitment of Armitage and Yb to a transcript triggers its phased processing into primary piRNAs in Drosophila ovaries.

Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function.

Characterization of the mammalian RNA exonuclease 5/NEF-sp as a testis-specific nuclear 3' → 5' exoribonuclease.

Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice.

PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway.

PIWI Slicing and RNA Elements in Precursors Instruct Directional Primary piRNA Biogenesis.

Metazoan Maelstrom is an RNA-binding protein that has evolved from an ancient nuclease active in protists.

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing.

Fly piRNA biogenesis: tap dancing with Tej.

Primary piRNA biogenesis: caught up in a Maelstrom.

RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts.

The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs.

Impact of nuclear Piwi elimination on chromatin state in Drosophila melanogaster ovaries.

Analysis of small RNA-guided endonuclease activity in endogenous Piwi protein complexes from mouse testes.

Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.

[The piRNAs forge an immune system for the genome].

Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc.

The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors.

A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing.

Molecular biology. Outsourcing genome protection.

piRNAs and their involvement in male germline development in mice.

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis.

Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a Piwi protein.

Artificial tethering of Argonaute proteins for studying their role in translational repression of target mRNAs.

The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs.

Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway.

The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.

Retrotransposon silencing by piRNAs: ping-pong players mark their sub-cellular boundaries.

Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile.

MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F.

Repression of protein synthesis by miRNAs: how many mechanisms?

Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells.

MicroRNA function: multiple mechanisms for a tiny RNA?

Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.

Inhibition of translational initiation by Let-7 MicroRNA in human cells.

The C-terminal domain of coilin interacts with Sm proteins and U snRNPs.

Post-transcriptional gene silencing by siRNAs and miRNAs.

The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein.

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis.

Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.

A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs.

Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.