Selected Publications

Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes.

Smyshlyaev G, Bateman A, Barabas O

Mol Syst Biol,2021 May17(5):

DOI: 10.15252/msb.20209880

A highly soluble Sleeping Beauty transposase improves control of gene insertion.

Querques I, Mades A, Zuliani C, Miskey C, Alb M, Grueso E, Machwirth M, Rausch T, Einsele H, Ivics Z, Hudecek M, Barabas O

Nat Biotechnol, 2019 Dec; 37 (12): 1502-1512

DOI: 10.1038/s41587-019-0291-z

[ Pubmed ]

Jump ahead with a twist: DNA acrobatics drive transposition forward.

Arinkin V, Smyshlyaev G, Barabas O

Curr Opin Struct Biol, 2019 Dec; 59 : 168-177

DOI: 10.1016/j.sbi.2019.08.006

[ Pubmed ]

The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans.

Weng C, Kosalka J, Berkyurek AC, Stempor P, Feng X, Mao H, Zeng C, Li WJ, Yan YH, Dong MQ, Morero NR, Zuliani C, Barabas O, Ahringer J, Guang S, Miska EA

Genes Dev, 2019 Jan 1; 33 (1-2): 90-102

DOI: 10.1101/gad.319293.118

[ Pubmed ]

Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering.

Morero NR, Zuliani C, Kumar B, Bebel A, Okamoto S, Guynet C, Hickman AB, Chandler M, Dyda F, Barabas O

Nucleic Acids Res, 2018 May 4; 46 (8): 4152-4163

DOI: 10.1093/nar/gky235

[ Pubmed ]

Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.

Rubio-Cosials A, Schulz EC, Lambertsen L, Smyshlyaev G, Rojas-Cordova C, Forslund K, Karaca E, Bebel A, Bork P, Barabas O

Cell, 2018 Mar 22; 173 (1): 208-220.e20

DOI: 10.1016/j.cell.2018.02.032

[ Pubmed ]

Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.

Bebel A, Karaca E, Kumar B, Stark WM, Barabas O

Elife, 2016 Dec 23; 5 :

DOI: 10.7554/eLife.19706

[ Pubmed ]

Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering.

Voigt F, Wiedemann L, Zuliani C, Querques I, Sebe A, Mátés L, Izsvák Z, Ivics Z, Barabas O

Nat Commun, 2016 Mar 30; 7 : 11126

DOI: 10.1038/ncomms11126

[ Pubmed ]

Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc.

Voigt F, Reuter M, Kasaruho A, Schulz EC, Pillai RS, Barabas O

RNA, 2012 Dec; 18 (12): 2128-2134

DOI: 10.1261/rna.034967.112

[ Pubmed ]

Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection.

Barabas O, Ronning DR, Guynet C, Hickman AB, Ton-Hoang B, Chandler M, Dyda F

Cell, 2008 Jan 25; 132 (2): 208-220

DOI: 10.1016/j.cell.2007.12.029

[ Pubmed ]

Orsolya Barabas

2021

2019

2018

2016

2012

2008