Telomeric transposons are pervasive in linear bacterial genomes.

A novel mitochondrial pyruvate carrier inhibitor drives stem cell-like memory CAR T cell generation and enhances antitumor efficacy.

First full views of a CRISPR-guided system for gene insertion.

Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes.

Engineered Sleeping Beauty transposase redirects transposon integration away from genes.

Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes.

Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation.

A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.

Jump ahead with a twist: DNA acrobatics drive transposition forward.

A highly soluble Sleeping Beauty transposase improves control of gene insertion.

Snapshots of a genetic cut-and-paste.

The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans.

Effects of stably incorporated iron on protein phosphatase-1 structure and activity.

Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering.

Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.

Conjugative transposition of the vancomycin resistance carrying Tn1549: enzymatic requirements and target site preferences.

Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq.

Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.

Structural Determinants of Sleeping Beauty Transposase Activity.

Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering.

An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.

Structure of an Escherichia coli Hfq:RNA complex at 0.97 Å resolution.

Acquisition of an Archaea-like ribonuclease H domain by plant L1 retrotransposons supports modular evolution.

Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling.

Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc.

DNA recognition and the precleavage state during single-stranded DNA transposition in D. radiodurans.

Helicobacter Pylori's plasticity zones are novel transposable elements.

Resetting the site: redirecting integration of an insertion sequence in a predictable way.

Molecular shape and prominent role of beta-strand swapping in organization of dUTPase oligomers.

Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.

Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.

Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.

In vitro reconstitution of a single-stranded transposition mechanism of IS608.

Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection.

Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase.

Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins.

Crystallization and preliminary X-ray studies of dUTPase from Mason-Pfizer monkey retrovirus.

Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase.

Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.

dUTPase and nucleocapsid polypeptides of the Mason-Pfizer monkey virus form a fusion protein in the virion with homotrimeric organization and low catalytic efficiency.

Synthesis and stereochemistry of dispiro substituted pyridazines: application of ellipticity-absorbance ratio spectra for proving enantiomeric relationship by HPLC-CD/UV detection.