Publications
2022
Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species.
Transmission of chromatin states across generations in C. elegans.
2021
Mitotic chromosome condensation requires phosphorylation of the centromeric protein KNL-2 in C. elegans.
The FASTK family proteins fine-tune mitochondrial RNA processing.
Transgenerational inheritance of centromere identity requires the CENP-A N-terminal tail in the C. elegans maternal germ line.
Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing.
2020
Loss of histone H3.3 results in DNA replication defects and altered origin dynamics in C. elegans.
Adaptations for centromere function in meiosis.
2019
H3.3K27M-induced chromatin changes drive ectopic replication through misregulation of the JNK pathway in C. elegans.
2018
Differential Expression of Histone H3.3 Genes and Their Role in Modulating Temperature Stress Response in Caenorhabditis elegans.
2016
Structure of centromere chromatin: from nucleosome to chromosomal architecture.
Cell type-specific epigenome profiling using affinity-purified nuclei.
2015
Diversity in the organization of centromeric chromatin.
Cell type-specific affinity purification of nuclei for chromatin profiling in whole animals.
2014
Holocentromeres are dispersed point centromeres localized at transcription factor hotspots.
2012
Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling.
2010
MicroRNA-directed siRNA biogenesis in Caenorhabditis elegans.
2009
RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans.
2007
Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans.
Secondary siRNAs result from unprimed RNA synthesis and form a distinct class.
2006
Knocking out the Argonautes.
Cloning and expression of new microRNAs from zebrafish.