Using light to activate treatments in the right place

The Gasic group participated in a study lead by the groups of Prof. Nicolas Winssinger (section of Chemistry and Biochemistry) &  Prof. Monica Gotta (faculty of medecine) . Together, they developed a tool that uses light to precisely control the activity and localization of a molecule, enabling targeted drug action.

 

More about this discovery (UNIGE PRESS) :

https://www.unige.ch/medecine/en/public-outreach/media/light-activate-treatments-right-place

and here: 

von Glasenapp, V., C. Almeida, A., Chang, D. et al. Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability. Nat Commun 16, 1599 (2025). 

DOI: 10.1038/s41467-025-56746-5